A medical sensor that attaches to the skin like a temporary tattoo could
make it easier for doctors to detect metabolic problems in patients and
for coaches to fine-tune athletes' training routines. And the entire
sensor comes in a thin, flexible package shaped like a smiley face.
"We wanted a design that could conceal the electrodes," says Vinci
Hung, a PhD candidate in the Department of Physical & Environmental
Sciences at UTSC, who helped create the new sensor. "We also wanted to
showcase the variety of designs that can be accomplished with this
fabrication technique."
The new tattoo-based solid-contact ion-selective electrode (ISE) is
made using standard screen printing techniques and commercially
available transfer tattoo paper, the same kind of paper that usually
carries tattoos of Spiderman or Disney princesses. In the case of the
sensor, the "eyes" function as the working and reference electrodes, and
the "ears" are contacts for a measurement device to connect to.
Hung contributed to the work while in the lab of Joseph Wang, a
distinguished professor at the University of California San Diego. She
worked there for six months earlier this year under the Michael Smith
Foreign Study supplement from NSERC.
"It was a wonderful opportunity," Hung said. She worked directly with
Wang, who is well-known for his innovations in the field of
nanoengineering and is a pioneer in biosensor technology.
The sensor she helped make can detect changes in the skin's pH levels
in response to metabolic stress from exertion. Similar devices, called
ion-selective electrodes (ISEs), are already used by medical researchers
and athletic trainers. They can give clues to underlying metabolic
diseases such as Addison's disease, or simply signal whether an athlete
is fatigued or dehydrated during training. The devices are also useful
in the cosmetics industry for monitoring skin secretions.
But existing devices can be bulky, or hard to keep adhered to
sweating skin. The new tattoo-based sensor stayed in place during tests,
and continued to work even when the people wearing them were exercising
and sweating extensively. The tattoos were applied in a similar way to
regular transfer tattoos, right down to using a paper towel soaked in
warm water to remove the base paper.
To make the sensors, Hung and her colleagues used a standard screen
printer to lay down consecutive layers of silver, carbon fiber-modified
carbon and insulator inks, followed by electropolymerization of aniline
to complete the sensing surface.
By using different sensing materials, the tattoos can also be
modified to detect other components of sweat, such as sodium, potassium
or magnesium, all of which are of potential interest to researchers in
medicine and cosmetology.
Journal Reference:
- Amay J. Bandodkar, Vinci W. S. Hung, Wenzhao Jia, Gabriela Valdés-Ramírez, Joshua R. Windmiller, Alexandra G. Martinez, Julian Ramírez, Garrett Chan, Kagan Kerman, Joseph Wang. Tattoo-based potentiometric ion-selective sensors for epidermal pH monitoring. The Analyst, 2013; 138 (1): 123 DOI: 10.1039/C2AN36422K
Courtesy: ScienceDaily
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